Biochip Screening

Biochip analysis with a microspectrophotometer

Microspectrophotometers are used to analyze biochip test points by reflectance, absorbance and fluorescence

 Biochip analysis with a microspectrophotometer

Typical test spectra

 

 

Rapidly screen microscopic test sites on biochips with reflectance or fluorescence microspectroscopy.

Biochip devices are a collection of microscopic test sites arranged in microarrays. This allows for many tests to be performed at the same time with a single device.  Biochips can be designed to replicate a series of full-scale chemical and biological reactions as microfluidic devices.  As such, a single device is used to  perform many chemical reactions but on a microscopic scale.  Therefore analytical techniques are required that can measure whether reactions have reached a successful conclusion but of micro-scale volumes.

Due to the microscopic volumes of the materials to be analyzed, microspectrophotometers are the perfect tool.  Able to analyze numerous micro-scale volumes by absorbance, reflectance or even fluorescence, these tools are easy-to-use and very accurate.  Their flexibility and accuracy make them very importance when developing or using custom biochip devices. 

To learn more about microspectroscopy and biochip device development and testing, select one of the following links: 

What is a Microspectrophotometer?

Science of Microspectrophotometers

Microspectrophotometer Design

Uses of Microspectrophotometers

20/30 PV™ Microspectrophotometers

 UV-visible-NIR microscopes, UV-visible-NIR microspectrometers and Raman microspectrometers are general purpose laboratory instruments. They have not been cleared or approved by the European IVD Directive, the United States Food and Drug Administration or any other agency for diagnostic, clinical or other medical use.

 

The Microphotometer is designed to measure the luminous intensity of microscopic samples or microscopic areas of larger objects.  The photometer unit is designed to attach to an open photoport of an optical microscope. Depending upon the configuration, it is capable of measuring the light intensity of microscopic samples by transmission, absorbance, reflectance, fluorescence, emission and polarization illumination.  

A CRAIC Technologies™ microphotometer is a purpose-built system that allows you to analyze UV-visible-NIR range optical intensity non-destructively and with no sample contact.  Capable of analyzing even sub-micron areas, they are also capable of color digital imaging.  Designed for ease-of-use, they are durable instruments designed for microscale analysis.

Contact CRAIC Today!

To learn more about microphotometry and microphotometers, select one of the following links: 

Science of microphotometry

Microphotometer Design

Uses of Microphotometers

CRAIC MP-2™ Microscope Photometers


We invite you to discover our revolutionary technologies that include a range of microphotometers, microspectrophotometers, UV-visible-NIR microscopes, Raman microspectrometers, Traceable Standards, microphotometer accessories and software. We further invite you to experience our exceptional service and technical support.

 

  

Microspectrophotometer

Microspectrophotometer

 

 

Microspectrophotometer

Emission Spectra Measured with a Microspectrophotometer

 

 

The Microspectrophotometer measures the UV-visible-NIR, emission and Raman spectra of microscopic samples.

Microspectrophotometers are designed to measure UV-visible-NIR spectra of microscopic samples or microscopic areas of larger objects.  There are two basic types: the fully integrated microspectrophotometer (as shown) that has been built and optimized for spectrophotometry.  There is also the spectrophotometer unit designed to attach to an open photoport of an optical microscope.   Each has its strengths and depending upon the configuration, both are capable of measuring the spectra of microscopic samples by transmission, absorption, reflectance, fluorescence, emission and polarization spectrophotometry.   With special software, both are capable of #D mapping measurements and micro-colorimetry as well.

A CRAIC Technologies™ microspectrophotometer is a purpose-built system that allows UV-visible-NIR range microspectrophotometry both non-destructively and with no sample contact.  Capable of analyzing even sub-micron areas, they are also capable of high resolution digital imaging.  Designed for ease-of-use, they are durable instruments designed for microscale spectroscopy.

Contact CRAIC Today!

To learn more about microspectrophotometers, select a link:

What is a Microspectrophotometer?

Science of Microspectrophotometry

Uses of Microspectrophotometers

20/30 PV™ Microspectrophotometer

508 PV™ Microscope Spectrophotometers

CRAIC Apollo™ Raman Microspectrometer

  

We invite you to discover our revolutionary technologies that include a range of microscope spectrophotometers, microspectrophotometers, UV-visible-NIR microscopes, Raman microspectrometers, Traceable Standards, micro spectrophotometry accessories and software. We further invite you to experience our exceptional service and technical support.

 

Micro Raman Spectroscopy

Micro Raman spectroscopy is a technique that uses a specialized Raman spectrometer to measure the Raman spectra of microscopic samples. In general terms, a Raman spectrometer is integrated with a Raman microscope. Different excitation laser wavelengths may be used to excite a microscopic sample so that the micro Raman spectrometer can collect and analyze the vibrational spectra. To learn more about the science of micro Raman spectroscopy, the micro Raman spectrometer instruments or how they are used, please click on the following links:

The Science of Micro Raman Spectroscopy

How a Micro Raman Spectrometer is Used

CRAIC Apollo™ Micro Raman Spectrometers

CRAIC Artemis Raman Spectrometers

 

Contact CRAIC Today!

We invite you to discover our revolutionary technologies that include a range of UV-visible-NIR microspectrophotometers, UV and NIR microscopes, micro Raman spectrometer, NIST Traceable Standards and specialized software. We further invite you to experience our exceptional service and technical support.

 

 

 

 

Thin film thickness measurement

 

 

 

Thin Film Measurement

Typical test spectra from for thin film thickness

Industries that use film thickness measurements include:

  • Optics
  • Semiconductor
  • Films on stents
  • and much more....

Small spot thin film thickness measurement can be done both by transmission and reflectance..

Thin film thickness measurement is done to monitor the thickness of thin films for a number of reasons.  These include such diverse industries as semiconductor integrated circuit manufacturing, anti-reflective coatings on optics, protective coatings and many more.  In all of these cases, it is critical to have consistent thickness of the films that are being deposited on the surface.  This can be done by acquiring the transmission or reflectance spectrum of a microscopically small area and calculating the thickness of the film.  This can be done for many locations on the item to map the changes in film thickness across the surface.

The CRAIC Technologies™ microspectrophotometer tools allow for non-destructive and non-contact thin film thickness measurement of sub-micron sized areas in both reflectance and transmittance. CRAIC instruments can also measure polarization anisotropy, optical emissions and even fluorescence. These flexible tools are equally at home in the R&D laboratory, the fab floor or the failure analysis facility. Currently, CRAIC solutions are used for film thickness measurement of semiconductors, LCD displays, OLED's, and optical products.

Contact CRAIC Today!

To learn more about thin film thickness measurement and how microspectrophotometers do it, select one of the following links: 

Thin Film Thickness Measurement Science

Thin Film Thickness Measurement Software

20/30 PV™ Thickness Measurement System


This e-mail address is being protected from spambots. You need JavaScript enabled to view it