Microarray Analysis

Microarray analysis with a microspectrophotometer

Microspectrophotometers are used to analyze microarrays by reflectance, absorbance and fluorescence

 

Microarray

Microspectra

 

 

UV-visible-NIR microscopy and microspectroscopy for analysis of any microarray.

Microarray devices are a collection of microscopic test sites arranged in arrays.  This allows for many tests to be performed at the same time with a single device.  Microarrays can be designed to replicate a series of full-scale chemical and biological reactions as microfluidic devices.  As such, a single device is used perform many chemical reactions but on a microscopic scale.  Therefore analytical techniques are required that can measure whether reactions have reached a successful conclusion but of micro-scale volumes.

.  Able to analyze numerous micro-scale volumes by absorption, reflectance or even fluorescence, microspectrometers are easy-to-use and very accurate. 

To learn more about microspectroscopy and microarray development and testing, select one of the following links:

What is a Microspectrophotometer?

Science of Microspectrophotometers

Microspectrophotometer Design

Uses of Microspectrophotometers

20/30 PV™ Microspectrophotometers

UV-visible-NIR microscopes, UV-visible-NIR microspectrometers and Raman microspectrometers are general purpose laboratory instruments. They have not been cleared or approved by the European IVD Directive, the United States Food and Drug Administration or any other agency for diagnostic, clinical or other medical use.

FPD Inspection

FPD or flat panel display

Microspectrophotometers are used to test the color and intensity of each FPD pixel


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FPD or flat panel display

Typical test spectra from a flat panel display

 

 

FPD Inspection: Color, chromaticity, luminance, spectroscopy and film thickness of pixels and light sources.

Flat Panel Display, or FPD, is a device that consist of a series of colored lighted areas arranged in a pattern.  Controlled with electronics, they can be used as light sources or as high resolution displays for everything from televisions to computers.  There are many different designs resulting in different quality control challenges. 

Due to the nature of flat panel displays, they are manufactured with hundreds of rows of microscopic "pixels" on a surface.  In the next generation of FPD, such as those used in MP3 players and mobile phones, these pixels can be as small as 10 microns across.  Quality control of both the components and completed FPD devices is done by optical microspectroscopy.  Microspectrometers, such as those made by CRAIC Technologies, are used to measure the color and the intensity of the output from individual pixels, from groups of pixels and from the light sources.  They are can be used to map the color and intensity outputs of individual pixels or even entire displays.  This is important as manufacturers of flat panel displays need to make sure that all the different types of pixels are the same color and brightness.  A microspectrophotometer does this quickly and easily. 

To learn more about microspectroscopy and FPD analysis and testing, select one of the following links: 

What is a Microspectrophotometer?

Science of Microspectrophotometers

Colorimetry of Pixels and Displays

Relative Intensity Measurements

508 FPD™ Spectrophotometers for Microscopes and Probe Stations

 

Biotechnology Instrumentation

Biotechnology development with a microspectrophotometer

Microspectrophotometers are used to analyze biotechnology products by reflectance, absorbance and fluorescence

 

Biotechnology

Microspectra

 

 

UV-visible-NIR microscopy and microspectroscopy for analysis of biotechnology.

Biotechnology applies the principles of technology to biology: where the technological products and organisms are derived from biology and agricultural sciences.  Products resulting from biotechnology research are used in three major areas: agriculture, biofuels and environmental applications.  As such, biotechnology ranges from microarrays where thousands or millions of tests can be conducted on a single device simultaneously to bioengineering and bioremediation. 

Due to the microscopic volumes of the materials to be analyzed, microspectrophotometers are the perfect tool.  Able to analyze micro-scale volumes by absorption, reflectance or even fluorescence, these tools are easy-to-use and very accurate.  Their flexibility and accuracy make them very importance for analyzing everything from genetically engineered organisms to sophisticated microarrays. 

To learn more about microspectroscopy and biotechnology applications, select one of the following links: 

What is a Microspectrophotometer?

Science of Microspectrophotometers

Microspectrophotometer Design

Uses of Microspectrophotometers

20/30 PV™ Microspectrophotometers

 UV-visible-NIR microscopes, UV-visible-NIR microspectrometers and Raman microspectrometers are general purpose laboratory instruments. They have not been cleared or approved by the European IVD Directive, the United States Food and Drug Administration or any other agency for diagnostic, clinical or other medical use.

Biochip Screening

Biochip analysis with a microspectrophotometer

Microspectrophotometers are used to analyze biochip test points by reflectance, absorbance and fluorescence

 Biochip analysis with a microspectrophotometer

Typical test spectra

 

 

Rapidly screen microscopic test sites on biochips with reflectance or fluorescence microspectroscopy.

Biochip devices are a collection of microscopic test sites arranged in microarrays. This allows for many tests to be performed at the same time with a single device.  Biochips can be designed to replicate a series of full-scale chemical and biological reactions as microfluidic devices.  As such, a single device is used to  perform many chemical reactions but on a microscopic scale.  Therefore analytical techniques are required that can measure whether reactions have reached a successful conclusion but of micro-scale volumes.

Due to the microscopic volumes of the materials to be analyzed, microspectrophotometers are the perfect tool.  Able to analyze numerous micro-scale volumes by absorbance, reflectance or even fluorescence, these tools are easy-to-use and very accurate.  Their flexibility and accuracy make them very importance when developing or using custom biochip devices. 

To learn more about microspectroscopy and biochip device development and testing, select one of the following links: 

What is a Microspectrophotometer?

Science of Microspectrophotometers

Microspectrophotometer Design

Uses of Microspectrophotometers

20/30 PV™ Microspectrophotometers

 UV-visible-NIR microscopes, UV-visible-NIR microspectrometers and Raman microspectrometers are general purpose laboratory instruments. They have not been cleared or approved by the European IVD Directive, the United States Food and Drug Administration or any other agency for diagnostic, clinical or other medical use.

 

The Microphotometer is designed to measure the luminous intensity of microscopic samples or microscopic areas of larger objects.  The photometer unit is designed to attach to an open photoport of an optical microscope. Depending upon the configuration, it is capable of measuring the light intensity of microscopic samples by transmission, absorbance, reflectance, fluorescence, emission and polarization illumination.  

A CRAIC Technologies™ microphotometer is a purpose-built system that allows you to analyze UV-visible-NIR range optical intensity non-destructively and with no sample contact.  Capable of analyzing even sub-micron areas, they are also capable of color digital imaging.  Designed for ease-of-use, they are durable instruments designed for microscale analysis.

Contact CRAIC Today!

To learn more about microphotometry and microphotometers, select one of the following links: 

Science of microphotometry

Microphotometer Design

Uses of Microphotometers

CRAIC MP-2™ Microscope Photometers


We invite you to discover our revolutionary technologies that include a range of microphotometers, microspectrophotometers, UV-visible-NIR microscopes, Raman microspectrometers, Traceable Standards, microphotometer accessories and software. We further invite you to experience our exceptional service and technical support.